The protection of fattening pigs against foot and mouth disease with an oil-adjuyant vaccine
نویسنده
چکیده
A water-in-oil adjuvanted FMD vaccine was formulated and tested in weanling fattening pigs. Following inoculation by either the subcutaneous, intramuscular or intraperitoneal routes, the vaccine induced a rapid onset of immunity demonstrable by challenge as early as 7 days post-inoculation. Duration of immunity following a single inoculation at the time of weaning provided protection against chal lenge for at least the duration of the fattening period (4 months). The emulsion has low viscosity and high physical stability (>1 year); potency-stability of at least 8+ months after storage at 4°C was demonstrated by challenge.
منابع مشابه
The protection of fattening pigs against foot and mouth disease with an oil-adjuvanted vaccine : Studies on South American FMD virus strains
The performance of a trivalent oil-adjuvanted FMD vac cine formulated with O1 Campos, A24 Cruzeiro and C3 Indaial FMD antigens has been evaluated in fattening pigs in Brazil. As previously demonstrated, a single dose of this type of vaccine injected at the time of weaning induced a rapid onset of protection against challenge and a protracted immunity lasting at least for four months, i.e. the ...
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